Why would elevated extracellular K decrease force output fro

Why would elevated extracellular K+ decrease force output from a muscle?

Solution

Extracellular K+ is regulated closely to maintain normal membrane excitability by the concerned regulatory responses of muscle and kidney. Although kidney is responsible for ultimately matching K+ output to K+ intake each day. Accumulation of extracellular K+ Indicates the reduction in dynamic contractile function during intense exercise. Depolarization occurs after a fast increase in extracellular k+ is dramatically slowed down.The depolarization induced by elevated extracellular K+ during the intense exercise is most likely to be much smaller than the depolarization induced by elevated by prolonged exposure of muscles to the same level of extracellular K+. This prolonged elevations in extracellular K+ or during extensive build up of extracellular K+, acidosis may have a role as a safety mechanism that tends to maintain excitability.