In untreated insulindependent diabetes which of the followin
In untreated insulin-dependent diabetes, which of the following reactions/pathways is accelerated, possibly resulting in toxic effects by the end product(s)? Conversion of cholesterol to progesterone Citric add cycle Conversion of 3-hydroxy-3-methylglutaryl CoA to acetoacetate Synthesis of cholesterol Click if you would like to Show Work for this question: By accessing this Question Assistance, you will learn while you earn points based on the Point Potential Policy set by your instructor.
Solution
Answer:C
Acetoacetate is a ketone body synthesize in the liver,l conditions like starvation, or low level of insulin in uncontrolled diabetes stimulate the enzyme HMG Co A synthase which lead to synthesize HMG Co A from acetoacetyle Co A. In the synthesis of ketone body a HMG Co A cleaved by HMG Co A lyase enzyme in to acetocetate which is toxic substance.
