What is the chemical basis for the specificity of binding an

What is the chemical basis for the specificity of binding an immunoglobin antibody to a particular antigen?

Solution

Antibodies bind antigens by weak chemical electrostatic interactions, and bonding is generally non-covalent in nature.Each antibody is capable of binding only to a specific antigen. The specificity of the binding is due to specific chemical composition of each antibody due to its unique amino acid sequences. Specific binding results come from the complementarity interactions between the antigen and the antigen locking site of the antibody by chemical properties like their size, charge and hydrophobicity.