Attenuation inhibits trp operon expression in conditions of

Attenuation inhibits trp operon expression in conditions of sufficient tryptophan levels via: terminating transcription terminating translation blocking co-repressor binding to trpR-encoded repressor Will attenuation occur under the following conditions? Give one-sentence rationale to your answer. Assume that these mutations disrupt base-pairing with partner regions. Region 2 mutated, tryptophan is low Region 3 mutated, tryptophan is high Uracil-rich region acquired several guanines, tryptophan level is high

Solution

The trp operon (tryptophan operon), is a collection of genes that encrypt biosynthetic enzymes for the tryptophan.

The trp operon is turned \"on\" (expressed) when the levels tryptophan are very low and high level turned \"off\" (repressed).

The trp operon is controlled through the trp repressor.

Combination of tryptophan and the trp repressor blocks expression of the operon.

So sufficient level of tryptophan terminating transcription