a for the following cell and Chanel dimensions and fluid and

(a) for the following cell and Chanel dimensions and fluid and cell properties , and for a wall shear stress of 1 dyn/cm2 acting on the lower plate, show that the Reynolds number for the leukocyte so is much less than unity: w=2cm, h=0.025cm, R(leukocyte)=0.0006cm, L=7.5 cm, leukocyte density = 1.07 g/cm3, density of medium= 1.01g/cm3 and u=0.0085g/cm.s
(b) state force balances acting on the cell in the x and y directions. Neglect any acceleration of the cell
(c) Solve the force balances to determine the distance traveled by a cell that is initially at the centerline.
(d) Discuss the effect of cell settling on the measurement of the adhesion of leukocyte so to lower plate under flow conditions

Solution

a parallel-plate fluid flow chamber is a benchop model that simulates fluid shaer stresses on various cell types exposed to dymanic fluid flow in their natural, physiological environment with the wall shear stress

a typical parallel-plate flow chamber consists of a polycabonate distriutor a silicon gasket and a glass coverslipbthe distributor forming one side of the parallel-plate flow chmber includes inlet port outlet port and a vacuum slot the thickness of the gasket ddetermines the height of the flow path. the glass coverslip forms another side of the parallel-plate flow chamber and can bee caoted with extracelluler matrix proteins vascular cells or biomaterials of interest a vacuum forms a seal to hold these three parts and ensure a uniform channel height

(a) for the following cell and Chanel dimensions and fluid and cell properties , and for a wall shear stress of 1 dyn/cm2 acting on the lower plate, show that t

Get Help Now

Submit a Take Down Notice

Tutor
Tutor: Dr Jack
Most rated tutor on our site