Global alignment in the global sequence alignment what is th

Global alignment

in the global sequence alignment, what is the impact of the gap penalty

Solution

The gap penalty is a scoring system used in bioinformatics for the alignment of the sequence with any reference sequence, more accurately. It is also known as read against a reference genetic sequence. It menas wherever the sequence is not matching it will give a gap penalty and generally mutantion in your sequence are encountered by giving the gap penaity. The scoring that occurs in Gap Penalty allows for the optimization of sequence alignment in order to get the best alignment possible based on the reference sequence. Its impact in global sequnce alignment is very vast as we can avoid any error encountered by the replication machinery by seeing the alignment and we can avoid or correct the mutations generated by DNA replication process by seeing the gap penalty of the alignmnet.