A mutation causing an addition or a deletion of one base pai

A mutation causing an addition or a deletion of one base pair resulted in the production of a nonfunctional mutant protein. The sequences of the normal and mutant proteins are given below.

Normal: Met - Gly - Glu - Val - Asp

Mutant: Met - Gly - Lys - Ser - Ile - Lys - Trp - Arg - .....

Was this mutation cause by an insertion or a deletion?

Below, fill in the codons in the coding sequence of the mRNA that is translated into the mutant protein. If more than one codon is possible, just enter a single codon.

Solution

Normal protein sequence is given as: Met - Gly - Glu - Val - Asp

The mRNA sequence for this sequence will be: AUG GGU GAA GUU GAU

Mutant protein sequence is given as: Met - Gly - Lys - Ser - Ile - Lys - Trp - Arg - .....

he mRNA sequence will be 5\'- AUG GGU AAG UCU AUU AAA UGG .....

the sequence shoe=ws that transition and transversion mutation has taken polace by which purines are exchanged with either purines or pyrimidines and vice versa.