1 EPHEDRINE DRUG administered in IV solution The drug Ephedr

1) EPHEDRINE DRUG administered in IV solution.

The drug \"Ephedrine\" is administered in IV solution. The concentration of the drug is 2 mMol. The IV solution is buffered at pH= 7.4 The buffer has a concentration of 150 mMol ( 150 mM of KH2PO4 / 150 mM K2HPO4. The pKa of the drug ephedrine is 9.6. Will the drug have a negative, positive, or neutral?

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Solution

The ephedrine exists almost solely in the basic form. and it will be more non ionised in this buffer. So drug will be negative