What is the function of thrombin in hemostasis A It initiate

What is the function of thrombin in hemostasis? A) It initiates the intrinsic pathway of coagulation. B) It initiates the extrinsic pathway of coagulation. C) It converts fibrinogen into fibrin D) It acts as a potent vasoconstrictor to reduce blood loss. E) It dissolves the clot after the tissue has healed

Solution

Que 8:

The function of thrombin in hemostasis:

A) It initiates the intrinsic pathway of coagulation.

B) It initiates the extrinsic pathway of coagulation.

C) It converts fibrinogen into fibrin.

D) It acts as a potent vasoconstrictor to reduce blood loss.

E) It dissolves the clot after the tissue has healed.

Explanation:

- The intrinsic pathway is triggered by blood coming into contact with collagen fibers in the broken wall of a blood vessel. It is intrinsic because intiated by factor inside the blood vessels.

- The extrinsic pathway is triggered by chemical called tissue factor that is released by damaged cells.This patway is extrinsic becaues initiated by factor outside the blood vessels.

- Thrombin is a serine protease that converts fibrinogen into fibrin and plays crucial role in hemosatsis and thrombosis.

- It acts as a potent vasoconstrictor by narrowing of damaged blood vessels to reduce blood loss.

- Thrombin plays major role in wound healing.