BCD A EGH H shows feedback inhibition of A What initially ha

B-->C-->D

A-->

E--->G--->H.

H shows feedback inhibition of A. What initially happens to H if the enzymes that catalyses B--

-> C is inhibited?

What happens to A as a result?

What is the final effect on A?

B-->C-->D

A-->

E--->G--->H.

H shows feedback inhibition of A. What initially happens to H if the enzymes that catalyses B--

-> C is inhibited?

What happens to A as a result?

What is the final effect on A?

A-->

E--->G--->H.

H shows feedback inhibition of A. What initially happens to H if the enzymes that catalyses B--

-> C is inhibited?

What happens to A as a result?

What is the final effect on A?

The sequential feedback provides a control mechanism for a branched metabolic pathway. The characteristics of this pathway are;

Therefore, if the enzymatic reaction B to C is inhibited there is accumulation of H which inhibits the buildup of A.

If both the end products D and H are present in abundance this leads to build up of A which in turn inhibits the first committed step in the formation of A.

The sequential feedback provides a control mechanism for a branched metabolic pathway. The characteristics of this pathway are;

the end product of each branch inhibits the first enzymatic reaction of its own branch
there is accumulation of the last metabolite of the common pathway
inhibition of the common pathway if both end products are present in excess

Therefore, if the enzymatic reaction B to C is inhibited there is accumulation of H which inhibits the buildup of A.

If both the end products D and H are present in abundance this leads to build up of A which in turn inhibits the first committed step in the formation of A.

B-->C-->D A--> E--->G--->H. H shows feedback inhibition of A. What initially happens to H if the enzymes that catalyses B-- -> C is inhibited

BCD A EGH H shows feedback inhibition of A What initially ha

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