e adenine nucleotide translocase ADPATP translocase a transp
e adenine nucleotide translocase (ADP-ATP translocase), a transporter located in the inner mitochondrial membrane, transports ADP and ATP across the membrane. It is an antiporter. (Recall that these adenine nucleotides are negatively charged: ADP3 and ATP4 Phosphate translocase is also located in the inner mitochondrial membrane. It transports H and phosphate (H2PO4 across the membrane. It is a symporter. Answer parts (a), (b), (c), and (d) below (a) Which direction is ADP transported during times of active oxidative phosphorylation? O into the mitochondrial matrix O there is no net flow of ADP O out of the mitochondrial matrix (b) What drives the transport of adenine nucleotides? O the electrochemical gradient (membrane potential) o simple diffusion O transport is coupled with ATP hydrolysis
Solution
Answer to (a) is into the mitochondrial matrix.
Answer to (b) is the electrochemical gradient (membrane potential)
Answer to (c) is 1 ADP per 1 ATP
Answer to (d) is H+ and H2PO4- are transported into the matrix in a process driven by proton gradient.
