Acetylcholine is the neurotransmitter that is released by p

Acetylcholine is the neurotransmitter that is released by _ postganglionic axons that travel in the vagus nerve. When you apply exogenous acetylcholine, it should _ heart rate because of its interactions with the pacemaker cells. What do you predict will happen to force of contraction? _ Why?

Solution

Answer:

Acetylcholine is the neurotransmitter that is released by parasympathetic postganglionic axons that travel in the vagus nerve. When you apply exogenous acetylcholine, it should decrease heart rate because of its interactions with the pacemaker cells. What do you predict will happen to force of contraction? The force of heart contraction will decrease because of the activation of muscarinic receptors which causes potassium to pass from the channels in the muscle membrane and decrease of Ca2+ entry in the cell why?