Please answer 14 Match the experiments in the graph to one o

Please answer 1-4

Match the experiments in the graph to one of the four scenarios: cells A and B, fimbriae regulation, or cells C and D tox gene regulation in C. diphtheria

Solution

Answer

Expt 4 = D cells, outside the host with high iron.

Expt 2 = C cells, inside host with low Iron

Production of Diptheria Toxin is affected by two factors out of which one is the IRON Concentration. High amount of IRON activates the DtxR (Diptheria toxin repressor) gene that does not allow diptheria toxin transcription. thus in D cells when they are outside host in HIGH Iron concentration, there wont be any production of Toxin RNA, and hence low protein too as seen in Experiment No. 4. Opposite conditions (Inside host and low Iron) for C Cells show High mRNA and high Protein.

Expt 1 = B

Expt 2 = A