Look carefully at the pedigree drawn below and match it to o

Look carefully at the pedigree drawn below and match it to one of the choice given Write your answer on the line provided. Most likely, the trait being tracked in the family is: a) autosomal recessive b) autosomal dominant c) X-sex linked recessive Condition of Interest: Hemophilia Hemophilia is a blood clotting disorder in which one of the proteins needed to form blood clots is missing or reduced (commonly, protein known as Factor VIII). Individuals have difficulty blood clots forming blood clots following injury and may suffer significant blood loss from even minor cuts and bruises. Inheritance Pattern: Factor VII is an essential blood clotting protein which is formed by a normal allele found on the X chromosomes; hemophilia is caused by a lack of Factor VIII which results from a recessive allele found on the X chromosome. Remember because this is an X-linked disorder, when you identify genotypes in this pedigree, you must use that XX/XY notation and use superscripts with each X chromosome to indicate whether the \"H\" (normal) or \"h\" (hemophilia) allele is present. (Ex X^H Y = normal male) Hemophilia became known as the \"Royal disease\" after it suddenly cropped up in some of the descendents of Great Britain\'s Queen Victoria and spread through the royal families of Europe Queen Victoria and her husband Prince Albert had 9 children - 5 girls (Beatrice, Victoria, Alice, Helena, and Louise - none of whom were hemophiliacs) and 4 boys (Edward, Alfred and Arthur had normal blood clotting: their son Leopold, however was a hemophiliacs). Beatrice married a man named Henry and they had four children (sons Leopold and Maurice who were hemophiliacs, daughter Eugenie who was not a hemophiliac, and another son who was also not a hemophiliac). Eugenie married Alfonso XIII of Spain (non-hemophiliac) and they had 6 children (2 normal sons, 2 normal daughters and 2 hemophiliac sons One of those normal sons married a non-hemophiliac woman and gave birth to one son-a non-hemophiliac they named Juan Carlos (the reigning King of Spain). Draw your pedigree for Case Study #4 on the back of this page.

Solution

From the pedigree given, most likely the trait being tracked in this family is X-linked recessive.