Which of the following statements about the nuclear localiza

Which of the following statements about the nuclear localization signal is NOT true? The NLS is a stretch of amino acids near the C-terminus of nuclear proteins. The NLS enables a protein to pass through the nuclear pores and enter the nucleus. The NLS is a stretch of amino acids on the N-terminus of nuclear proteins. If one of the basic amino acids of the NLS is replaced a nonpolar amino acid, the protein is incorrectly localized.

Solution

The correct answers is :If one of the basic aminoacids of the NLS is replaced a nonpolar acid, the protein is incorrectly localised.

Reason: NLS sequence may contain either stretches of lysines or arginine residues.Deletion of the sequence may result in incorrect localization but replacement with a non polar aminoacid will not result in incorrect localization.