Imagine a two allele system A where the fitness values for t

Imagine a two allele system (A) where the fitness values for the three genotypes are w₁₁=0.8; w₁₂=0.8; w₂₂=0 and another (B) where the fitness values are w₁₁=0.83; w₁₂=0.8; w₂₂=0.

Will A or B have the highest equilibrium frequency? Why?

Solution

Selection coefficient (s) = 1 - the relative fitness
For (A) the fitness values are w11=0.2; w12=0.2; w22=1
For (B) the fitness values are w11=0.17; w12=0.2; w22=1.

Predicting that the B allele will decrease in frequency over time, then A allele has the highest equilibrium frequency.