A person who smokes for the first time tends to experience m
     A person who smokes for the first time tends to experience much more severe effects from a cigarette than does someone who smokes frequently. Given that the smoke contains nicotine, provide a reasonable explanation for this difference.  Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Not all terms will be used.   
  
  Solution
Smokers DO develop tolerance to nicotine. Therefore, it would be reasonable to suggest that CHRONIC exposure to nicotine might lead to RECEPTOR DOWN REGULATION as a basis for this tolerance.

