How can different cells respond in different ways to exactly
How can different cells respond in different ways to exactly the sam emolecules even when those molecules are binding to the same receptors? Provide an example
Solution
Beacause of several reason
1-down stream of cell receptor in another cell have diffrent secontry massenger .
2- concentration of signal molecuel also matter its also lead to different respond.
3-Due to varient in receptor.
example
Wnt signaling in mouse embryonic stem cell
Wnt signaling is very well known for inducing diffentiation pathway and decrease proliferation
Wnt activate beatcatenin and induce difrentiation
where as same wnt signaling in cancer stem cell active MEK pathway and increase cloning of cancer stem cell,and increase proliferation
