One thousand minis are recorded from a mammalian NMJ and the

One thousand minis are recorded from a mammalian NMJ, and the average amplitude is 0.5 mV. At the NMJ of an adjacent fiber, a similar recording gives an average of 1.0 mV. What is the most likely explanation of this disparity?

Solution

Answer

The disparity in the amplitude is due the triggering of action potential in the adjacent fibre membrane. In almost all mammalian/human NMJ, the junction takes from of a motor endplate but less extensive structures occur in other locations.Thus, there would be a great disparity in the amplitude.