For the following fragment of DNA determine 5ACGTAGAGTGCTC3
     For the following fragment of DNA, determine:  5\'-ACGTAGAGTGCTC-3\'  3\'-TGCATCTCACGAG-5\'  the number of hydrogen bonds present. 
  
  Solution
Step I: To get an idea of the number of hydrogen bonds between bases
Number of hydrogen bonds between AT = 2 hydrogen bonds
Number of hydrogen bonds between GC = 3 hydrogen bonds
Step II: Observe the fragment carefully and identify the bonds
Six AT bonds and Six CG bonds
Step III: Calculate
6x2 + 6x3 = 30
So number of hydrogen bonds present is 30

