Biochemistry What is the biochemical advantage of having a K

Biochemistry-:

What is the biochemical advantage of having a KM approximately equal to the substrate concentration normally available to an enzyme?

Solution

K_m is the Michaelis-Menten constant that shows concentration of the substrate when the reaction velocity is equal to one half of the maximal velocity for the reaction. K_m measure how well a substrate complexes with a given enzyme,also known as its binding affinity.

                                 K_m = [S],      r = 1/2 V_max

K_m is equal to that concentration of substrate at which rate of formation of product is half the maximum rate obtained at high concentarion of substrate.

Biochemical advantage of having a KM approximately equal to the substrate concentration normally available to an enzyme means enzyne is showing that enough catalysis is yet senstive to change in substrate concentration.