The disease Adrenoleukodystrophy ALD occurs when there is an

The disease Adrenoleukodystrophy (ALD) occurs when there is an accumulation of long fatty acid chains in the body. ALD results in neurodegeneration and problems with vision, hearing, and motor coordination.

In Drosophila, the bubblegum gene is similar to the human gene that when mutant causes ALD. Mutations in bubblegum result in fly vision defects. Mutations in the curly gene result in curly wings.

You want to study the linkage between bubblegum and curly so you do this cross:

Wild type female : bgm+ bgm cu cu+

Curly winged vision defects male: bgm bgm cu cu

You get 395 Wild type,

405 curly winged vision defects,

99 vision defects with normal wings

101 curly wings with normal vision

What is the map distance between bubble gum and curly?

A.9.9 cM

B.10.1 cM

C.20.0 cM

D.39.5 cM

E.40.5 cM

Solution

option (c) 20.5 cm

In Drosophila, the bubblegum gene is similar to the human gene that when mutant causes ALD. Mutations in bubblegum result in fly vision defects. Mutations in the curly gene result in curly wings.