From a17 carbon Fatty acid how many TOTAL ATP will you make

Solution

From a 17 Carbon Fatty Acid the total ATP formed are:

Activation of the fatty acid to Acyl CoA = -2 ATP

Number of rounds in the Beta oxidation

(17/2) -1.5 = 8.5-1.5 = 7

7 rounds x 5 ATP/ round = 35 ATP

Number of units of Acetyl CoA produced = 7 Acetyl CoA

7 Acetyl CoA x 12 ATP/Acetyl CoA = 84 ATP

Propionyl CoA up to Succinyl CoA = -1ATP

Succinyl CoA up to Malate = 3 ATP

Malate up to Pyruvate (1 NADPH.H+)

Pyruvate up to Acetyl Co A = 3 ATP

Acetyl CoA oxidation in the Krebs Cycle = 12 ATP

Total of ATP (considering the total oxidation of Propionyl CoA converted to Malate and then from Malate to Pyruvate and then from Pyruvate to Acetyl CoA = -2 + 35 +84 -1 + 3 +3 +12 = 134 ATP,

So total number of ATP\'s formed are 134 ATP.