Proofreading and repair of the DNA double helix does NOT inv

Proofreading and repair of the DNA double helix does NOT involves a. a. detecting a mis-match in base pairs. b. removing the mis-match with a nuclease. c. annealing the Okazaki fragments together with DNA ligase. d. repairing the mis-match with polymaerase. e annealing the edited DNA with the rest of the molecule with ligase.

Solution

DNA proof reading is a mechanism to correct errors during DNA replication and to repair DNA damage during a cell\'s life time. Cells have a variety of mechanisms to prevent mutations or permanent changes in DNA sequence.

DNA polymerases check their work by fixing the majority of mispaired bases in a process called proof reading.

After DNA synthesis any mispaired bases can be replaced in a process called Missouri match repair.

If DNA gets damaged, it can be repaired by various mechanisms including chemical reversal, excision repair and double stranded break repair.

It does not involves the annealing the okazaki fragments together with DNA ligase.