Describe how an SSRI worksSolutionSSRI Selective serotonin r

Describe how an SSRI works

Solution

SSRI- Selective serotonin reuptake inhibitor

These are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders. Exact mechanism of its mechanism is not known yet but believed to increase the extracellular level of the neurotransmitterserotonin by limiting its reabsorption into the presynaptic cell, increasing the level of serotonin in the synaptic cleft available to bind to the postsynaptic receptor. They have varying degrees of selectivity for the other monoamine transporters, with pure SSRIs having only weak affinity for the norepinephrine and dopamine transporters.