Methylation of residues in mammals is associated with Aden

Methylation of _______ residues in mammals is associated with __________

Adenosine/DNA repair

Cytosine/DNA repair

Adenosine/transcriptional repression

Cytosine/transcriptional repression

Cytosine/transcriptional activation

Solution

Answer:

Methylation of Cytosine residues in mammals is associated with transcriptional repression.

Explanation: DNA methylation may affect the transcription of genes in two ways. The methylation of DNA itself may physically impede the binding of transcriptional proteins to the gene, or
methylated DNA may be bound by proteins known as methyl-CpG-binding domain proteins

methylated DNA may be bound by proteins known as methyl-CpG-binding domain proteins.DNA methylation is a powerful transcriptional repressor, at least in CpG dense contexts.