explain the type of research design that was used in this st

explain the type of research design that was used in this study. Summarize your source, and be sure to include an explanation of the following questions in your response:

Is it evident that primary, secondary, or meta-analysis was used?

What role did surveys play, if any? Explain.

Were there any flaws or discrepancies in the data? Why or why not?

Volume 23, Number 11—November 2017

Dispatch Long-Term Viruria in Zika Virus–Infected Pregnant Women, Brazil, 2016

Terzian, A. B., Estofolete, C., Alves da Silva, R., Vaz-Oliani, D., Oliani, A., Brandão de Mattos, C....Nogueira, M. L. (2017). Long-Term Viruria in Zika Virus–Infected Pregnant Women, Brazil, 2016. Emerging Infectious Diseases, 23(11), 1891-1893. https://dx.doi.org/10.3201/eid2311.170078.

Solution

Primary analysis: zika virus screening of RNA samples were performed on urine samples of pregnant women during different stages of pregnancy. Positive and negative samples were detected along with three newborns had adverse outcomes.

Secondary analysis: quantitative real time Pcr, fluorescent based PCR with primers targeting the zika virus envelope were used to detect the viral load.

Meta analysis: the screening method is being utilise in the large group of pregnant ladies by keeping a criteria of patients with Ct value less than or equal to 38.5 are considered positive and patient with more than ct value of 38.5 are considered negative for zika virus.

The main criteria kept for sample selection were pregnant women of 4-38 weeks into their pregnancy.

The survey was done on urine samples of patient where physiological stress is not given to females and the virus was getting detected after early onset of symptoms.

The entire of the procedure was considered highly workable approah with less biasness observed in the results.

The results need to verified with large group of population of pregnant ladies as to make statistical significant comment. The further research focus on relationship between viruria and outcomes of newborns.

Of the 12 newborns 3 had adverse outcomes, 1 had subependymal cysts and 2 had unilateral abnormal otoacoustic emissions.