Urinalysis question How can the presence of RBC casts along

Urinalysis question:

-How can the presence of RBC casts (along with WBC casts) differentiate between a kidney infection which is glomerular in origin from a kidney infection that is tubular in origin?

Solution

The presence of RBC casts (along with WBC casts) differentiate between a kidney infection which is glomerular in origin from a kidney infection that is tubular in origin via urineanalysis because urine casts are generated from the tubules are associated with “protein known as Tamm-Horsfall protein” in hotdog-like shape. These tubular casts are made of “non-clumped forms of red or white blood cells” with hyaline casts indicates infection in tubules. The glomerular infection can be denoted by “ball –shaped clumped forms of red or white blood cell casts with proteins” finally causes infectious inflammation trigger eventually waxy granular casts with hyaline matrix.