Which statement regarding geriatric pharmacology is false Se

Which statement regarding geriatric pharmacology is false?

Select one:

a. Decreased glomerular filtration rate can reduce renal elimination of many drugs.

b. Increased blood flow to the liver can improve metabolism of many drugs

c. Polypharmacy contributes to increased drug interactions and ADRs

d. Lower medication dosages may be required to compensate for age-related functional decline in organs.

Solution

Answer

The incorrect statement is option (b) - Increased blood flow to the liver can improve metabolism of many drugs.

A large blood flow to the liver will deliver enough amounts of drugs but alters the rate of metabolism. As the blow flow increases to the liver, the rate of removal of drug by the organ will also be increased. The drug will decrease its clearance activity and the GFR will also be decreased.