How does the arrival of a termination codon at the A site tr

How does the arrival of a termination codon at the A site trigger the end of protein synthesis? See Section 17.5 A special release tRNA binds at the A site and releases the polypeptide from the final tRNA to which it is bound. A protein release factor binds in the A site and releases the polypeptide from the final tRNA to which it is bound. The mRNA itself catalyzes the release of the polypeptide from the last tRNA. When the stop codon is reached the ribosomal subunits separate and the mRNA and polypeptide are released.

Solution

A protein release factor bound to A site and release the polypetptide from the final tRNA to which it is bound

Note-

The release factor take the place at A site and bind to stop codon releasing the newly formed polypeptide breakingthe bond between the tRNA and p site.

Thus releasing tRNA seprately polypeptide seprately and dissociating ribosome into small and larger parts