Which of the following is an amino acid side chains can rece

Which of the following is an amino acid side chains can receives a terminal phosphate from an ATP molecule?

Serine

Threonine

Tyrosine

None of the above

All of the above

Solution

Answer: E. All of the above

Explanation:

While phosphorylation is a prevalent post-translational modification (PTM) for regulating protein function, it only occurs at the side chains of three amino acids, serine, threonine and tyrosine, in eukaryotic cells. These amino acids have a nucleophilic (–OH) group that attacks the terminal phosphate group (-PO32-) on the universal phosphoryl donor adenosine triphosphate (ATP), resulting in the transfer of the phosphate group to the amino acid side chain.