DNA polymerase I has 53 polymerase activity 53 exonuclease a

DNA polymerase I has 5\'-3\' polymerase activity, 5\'-3\' exonuclease activity, and 3\'-5\' exonuclease activity necessary for DNA replication. Mutations in the gene that encodes DNA polymerase I may cause the enzyme to lose these activities. Match the consequence of a loss-of-function mutation in DNA polymerase I to the corresponding lost activity. Lost 5\'-3\' polymerase activity Lost 5\'-3\' exonuclease activity Lost 3\'-5\' exonuclease activity

Solution

DNA polymerase - 1 has three parts the smaller part and bigger parts called Klenow fragments...!!!

Loss of 3\'-5\'- exonuclease activity...!!

(a) decrease in the polymerase fidelity.. (as it main function is to mediates proofreading)..

Lost 5\'-3\'polymerase activity...!!

(a) No DNA synthesis to fill gaps caused by the removal of the RNA... (as it main function is to synthethis of the DNA strands)..

Loss of 5\'-3\' exonuclease activity...!!

(a) No RNA primer removal during DNA..