Survivin Monomer Plays an Essential Role in Apoptosis Regula

Survivin Monomer Plays an Essential Role in Apoptosis Regulation Marat S. Pavlyukov, Nadezhda V. Antipova, Maria V. Balashova, Tatjana V. Vinogradova, Evgenij P. Kopantzev, and Mihail I. Shakhparonov1

What hypothesis is proposed by the authors in the above study?

Solution

Survivin monomer was unable to dimerize and can interact with smac/ DIABLO both in vivo and in vitro.Our hypothesis further suggested that survivin can bind to XIAP and protect cells from death.