Can you explain why Chargaffs rule doesnt apply to RNA And a

Can you explain why Chargaff\'s rule doesn\'t apply to RNA. And also I am confused about complementary base pairing in RNA, because it doesn\'t have a double helix, does it still pair up? If not, why is it said that A pairs with U and G pairs with C?
Can you explain why Chargaff\'s rule doesn\'t apply to RNA. And also I am confused about complementary base pairing in RNA, because it doesn\'t have a double helix, does it still pair up? If not, why is it said that A pairs with U and G pairs with C?

Solution

Answer:

Actually, RNA does not obey the Chargaff\'s rule as it does not have double helix. But some viruses have double standed RNA, where the RNA obeys Chargaff\'s rule . Based on that the pairing of nucleotides was identified.

A-U

G-C

Can you explain why Chargaff\'s rule doesn\'t apply to RNA. And also I am confused about complementary base pairing in RNA, because it doesn\'t have a double he

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