Using 10 amino acids as building blocks propose a sequence f

Using 10 amino acids as building blocks, propose a sequence for an integral protein. Your sequence must have a transmembrane portion of a length of 6 amino acids, and you must have at least 2 amino acids inside and 2 outside the cell. Draw and label your polypeptide with respect to the plasma membrane (you can use abbreviations and you do not need to draw the molecular structures)

Solution

Asparagine- glutamine—Glycine – Alanine – Valine –Isoleusine – Leusine-Methionine-Leusine –Alanine

Outer surface should have hydrophilic amino acids residues

Asparagine and Glutamine

Integral part should have hydrophobic residues

Glycine – Alanine – Valine –Isoleusine – Leusine-Methionine

Inner part should have hydrophobic residues

Leusine –Alanine