1 The probabilities of three genotypes XX XY and YY are thet

1. The probabilities of three genotypes XX, XY and YY are theta^2, 29(1 - theta) and (1 - theta)^2 for some theta. In a study of 3.000 individuals, the frequencies of the three genotypes are: genotype XX XY YY Frequency 1846 777 377 The maximum likelihood estimate for theta is 0.7281 Which of the following is a 10% significance region for theta, based on the chi-squared statistic Sigma (Xi =E(Xi))^2/E(Xi) : (i) [0.7137,0.7410] (ii) [0.7201,0.7322] (iii) [0.7201,0.7359] (iv) [0.7235.0.7322]

Solution

(III) is correct

 1. The probabilities of three genotypes XX, XY and YY are theta^2, 29(1 - theta) and (1 - theta)^2 for some theta. In a study of 3.000 individuals, the frequen

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