Which of these molecules would not be an effective drug to t

Which of these molecules would not be an effective drug to treat rheumatoid arthritis. Methotrexate: an immune system suppressant Enantercept; a free TNF-alpha receptor Pembrolizumab: anti-PD1 antibody Rituximab: an anti-CD20 antibody

Solution

Rhematoid arthritis is an autoimmune disorder. It is a condition where the some cells of the body cause destruction of the own body cells( self cells) trigerring inflamation.

There is no cure for Rheumatoid arthritis as it is an autoimmune disorder. But current treatment using drugs or medicines reduce the symptomps severity. The current classes of drugs include

Pembrolizumab is not an effective drug to treat rheumatoid arthritis. This drug targets programmed cell death 1( PD1) receptor. It binds and blocks to the PD1 receptor on lymphocytes . It inhibits PD1 and destroys cancer cells. Hence is a drug to treat cancer. It is used in cancer immunotherapy.

Disease-modifying antirheumatic drugs (DMARDs) - These include methotrexate , leflunomide , hydroxychloroquine and sulfasalazine . These drugs slow the progression of rheumatoid arthritis. They also protect further damage to the bones.