Select all true statements regarding competitive inhibitors

Select all true statements regarding competitive inhibitors. Prevents binding of substrate to enzyme. Could be used as a therapeutic agent in some cases. Do not decrease the apparent V_max of an enzyme. Can decrease the apparent K_m of an enzyme.

Solution

The true statements are :

Reason: When competitive inhibitors bind to enzyme, that prevents binding of substrate to the enzyme.Also,Vmax does not change and remains the same.However,Km becomes increased as the affinity of enzyme for the substrate is decreased.Some competitive inhibitors are also used as therapeutic drugs such as Tamiflu , para aminobenzoic acid etc.