Using a simple Punnett Square and assume no variables exist

Using a simple Punnett Square and assume no variables exist Work this problem and submit your work by email or bring the day of the test: A genetic disease is found to be Autosomal Dominant. What is the probability of a heterozygous father and homozygous mother having a child with the disorder? A genetic disease is found to be Autosomal Recessivet. What is the probability of a heterozygous father and heterozygous mother having a child with the disorder?

Solution

A. It is dominant autosomal so heterozygous also would be having disorder. Heterozygous father (Aa) and homozygous mother (aa)

so half (1/2) or 50% of child would be having disorder. Now as here it is not clear that mother is homozygous for reccesive or dominant. I took as reccesive. suppose if she is having dominant homozygous then in such case 100 % would be shown disorder.

B. It is autosomal recessive. so only with homozygous dominant would showing disorder.

Father is Aa and mother Aa

so in such case 1/4 that is 25 % would be having disorder.

	a	a
A	Aa	Aa
a	aa	aa