Cell Physiology Discuss the synthesis and fate of cytosolic

Cell Physiology: Discuss the synthesis and fate of cytosolic, membrane-bound and secretory proteins

Solution

Answer:-The cytosolic proteins are synthesised on free free ribosomes. There fate depends on some basic amino acid signal for example NLS nuclear localization signal that directs the cytoplasmic protein to get localizednwothin nucleus.

Membrane bound protein :-Many proteins after being translated in the cytosol are attached with specific fatty acids and are then anchored with lipid bilyaer of different cell organelles. The most common membrane attached proteins are GTP binding protein, RAS etc.

Secretary proteins:- Secretary proteins are synthesised in the cytosol the are directed into ER where they undergo folding and modifications. From ER they are transported into vesicles into Golgi complex here further tagging and modification occurs. After this Secretary proteins are budded off in the form of vesicles to their site of action. Fro example hormones, enzymes, toxins etc.