Answer all FIVE below biology question without copying from

Answer all FIVE below biology question without copying from any online sources.

Are most proteins unique, or built up from existing domains? Why? What are the advantages to quaternary structure over having a single long polypeptide chain? Are NAD- and ATP-binding domains generally conserved or unique? Why? Why do proteins have cofactors (what role do they serve)? Describe the two ways proteins can interact with DNA, and the differences between both Which is similar to the RNA recognition motif? What is the purpose of the dozens of p53 modifications?

Solution

Most proteins are built from existing domines.As nature is a thinker and not an inventor, new sequences are adapted from pre-existing sequences rather than invented.Molecular evalution gives rise to families of related proteins with similar sequences and structure. There are currently about 110,000 expermentally determined protein 3D structures deposited within the Protein Data Bank(PDA). However, this set contains many identical or very similar structures. All proteins should be classified to structural families to understand their evolutionary relationships.