QUESTION 11 During an outbreak of varicella 250 school child
QUESTION 11
During an outbreak of varicella, 250 school children were investigated.
Of these, 125 met the case definition. Of the children who did not get sick, 80% were vaccinated for varicella. Of the children that were sick, 10% were vaccinated.
Construct a 2x2 table in the following manner. Use the chart to answer the following question:
The value of the most appropriate measure of association (Relative Risk or Odds Ratio) is:
Sick
Not Sick
Total
Vaccinated (exposed)
P
Q
Total vaccinated
Not Vaccinated
(not exposed)
R
S
Total not vaccinated
Total
Total sick
Total not sick
0.444
0.028
0.375
0.128
0.5 points
QUESTION 12
You are following a group of people with occupations requiring them to work primarily outdoors to determine if their exposure to ticks, mosquitoes, and other insects increases their likelihood of contracting a vector borne disease.
What type of study is it?
a.
Ecological
b.
Cross Sectional
c.
Case Control
d.
Cohort Study
e.
Experimental
0.5 points
QUESTION 13
Outbreaks of the Ebola virus infection have occurred since 1976. Ebola has high infectivity and mortality in humans.
Ebola epizootic has also been devastating to other animals and caused large number of deaths, in thousands and caused devastation in which of these animal population?
Domestic Cats
Fish
Giraffes
Gorillas
Zebras
Lions
0.25 points
QUESTION 14
Consider a cohort of 5 initially disease-free subjects being studied over a 5 year period as follows:
Subject 1: Joins at the start of the study, remains disease free for 5 years
Subject 2: Joins at the start of the study, develops disease after 3 years
Subject 3: Joins at year 3, remains disease free for 2 years
Subject 4: Joins at year 2, develops disease after 1 year
Subject 5: Joins at the start of the study, lost to follow-up after 2 years
The total person-years contributed by those at risk for the outcome, for this study is:
a.
5
b.
25
c.
13
d.
4
points
QUESTION 15
A hospital in rural Maine noted that there were 32 reported infections associated with 1,596 surgeries performed last year. The hospital reported 4012 discharges last year.
The most appropriate measure of these hospital associated infections would be:
a.
Risk adjusted infection rate
b.
Crude infection rate
c.
Adjusted infection rate
d.
The number of infections reported. i.e. 32
0.5 points
QUESTION 16
The following 2x2 table is constructed for a cohort study of 460 people in a village for the risk of contracting malaria using bed nets.
Use the table to answer the following question:
Which is the most appropriate measure of association to use in this situation is Relative Risk or Odds Ratio?
Write your response in the space provided.
Maleria
No Malaria
Total
Use bed nets
12
264
276
Do not use bed nets
94
90
184
Total
106
354
460
0.5 points
QUESTION 17
Cumulative incidence refers to new cases that develop among initially disease-free individuals in a certain time period and allows for the unequal weightage of the study participants.
True
False
0.5 points
QUESTION 18
An example of a disease transmitted by fomites is:
Lyme Disease
Cholera
Dengue
Malaria
0.5 points
QUESTION 19
A disease that has been eradicated worldwide is:
a.
Trichuriasis
b.
Rabies
c.
Smallpox
d.
Schistosomiasis
e.
Lymphatic filariasis
0.5 points
QUESTION 20
In contrast to analytical study designs, descriptive study designs collect individual level data and compare the occurrence of disease with exposure.
True
False
0.5 points
QUESTION 21
During an outbreak of varicella, 250 school children were investigated.
Of these, 125 met the case definition. Of the children who did not get sick, 80% were vaccinated for varicella. Of the children that were sick, 10% were vaccinated.
Construct a 2x2 table in the following manner. Use the chart to answer the following question:
What is the value of “P”?
Sick
Not Sick
Total
Vaccinated (exposed)
P
Q
Total vaccinated
Not Vaccinated
(not exposed)
R
S
Total not vaccinated
Total
Total sick
Total not sick
104
30
108
12
| Sick | Not Sick | Total | |
| Vaccinated (exposed) | P | Q | Total vaccinated |
| Not Vaccinated (not exposed) | R | S | Total not vaccinated |
| Total | Total sick | Total not sick |
Solution
Question 11: 0.12
Question 12: Cohort study
Question 13: Gorilla
Question 14: 4
Question 15: Risk adjusted infection rate
Question 16: 460
Question 17: False
Question 18: Cholera
Question 19: smallpox
Question 20: False - As no environmental parameter is manipulated
Question 21:P is 12





