You get the following result from an electropherogram D21S11

You get the following result from an electropherogram: D21S11 28, 29. From other loci you determine that there are two people in the mixture. What are the possible genotypes that could account for the 28, 29 result at D21S11?

Solution

Answer:

An electropherogram is a plot of results from separation done by eletrophoresis.

Such plots are often acieved using an automated sequencer. In population genetics,

Out of many possibilities, it could be

(i) A mutation occurs when DNA is damaged or changed anywhere along the DNA strand. Mutations that occur in primer-binding site regions or along the STR region can complicate interpretation.

(ii) Mutations occurring during meiosis can affect the interpretation of paternity tests. A mutation during meiosis may result in discrepant results at a locus

(iii) Somatic mutations have been known to occur at STR loci used in forensic testing. A somatic mutation occurs within somatic cells and are not inherited.