In the extrinsic apoptotic pathway death ligands bind to dea

In the extrinsic apoptotic pathway, death ligands bind to death receptors. Which of the following is NOT a downstream result of this binding?

Clustering of receptors.

Binding of adaptor proteins such as FADD.

Activation of caspase 8.

Activation of caspase 1.

Activation of CAD.

Question 1 part A.)

Which of these enzymes begins the intrinsic caspase cascade?
      
Caspase 3

      
Caspase 7

      
Caspase 8

      
Caspase 9

Part B.)

Solution

First one answer is activation of Caspase1. Which is not found in extrensic pathway.

Second question answer is Caspase 9. Which is activated by cytochrome C and activates downstream molecule

Caspase 3 and leads to apoptosis.