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Solution

(1)Synaptic transmission begins with the arrival of an action potential at the presynaptic axon terminal. Arrival of action potential at the axon terminal depolarized the membrane causing opening voltage-gated Na+ channels.

(2)As the Na+ ions enter the cell, the membrane is more depolarized causing voltage-gated Ca2+ channels to open.

(3)Calcium influx initiates a signalling cascade resulting in fusion go synaptic vesicles with the postsynaptic membrane and release of neurotransmitters into the synaptic cleft. The calcium is removed from the cell and the membrane returns to normal resting potential

(4)The empty vesicles are recycled back and subsequently refilled with newly synthesized or recycled neurotransmitter.


(5)Released neurotransmitters bind to receptors on the postsynaptic cell and initiate action potential

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