I know that one of the main differences between the rough an

I know that one of the main differences between the rough and smooth endoplasmic reticulum is the presence or absence of ribosomes. The structures also have different shapes, rough ER is flat, and the smooth ER is more round.

My question is what specific process causes the two different forms of ER to divide and be so different? At what point does the ER decide to stop making ribosomes and begin to initiate the synthesis of smooth ER?

Solution

Answer :- The rough ER is specialized with function of protein synthesis and smooth ER with lipid synthesis. When cell is need of lipids and need less proteins the rough ER undergoes loss of ribosomes and gets transformed into smooth ER. ER are actually the membrane extensions of nuclear memebrane.