Ram is married to his uncles daughter Geeta and their daught

Solution

Ram is married to his uncle’s daughter Geeta and their daughter Reema was born with alkaptonuria an inherited metabolic disorder.

Ram i---------- normal -----GENOTYPE ========Aa

married to his uncle’s

Geeta--------- normal ------GENOTYPE ========Aa

Reema was born with alkaptonuria---------- GENOTYPE ========aa

Ram i---------- Aa           x       Geeta-------Aa

gamtes

A

a

A

AA normal

Aa normal carrier

a

Aa normal normal carrier

aa       affected

with alkaptonuria

Every issue is NEW AND INDEPENDENT EVENT

Ram and Geeta are however normal, but one of their grand parents had the same disease. The couple are planning to have their second child.

What is the probability of their next child being born with alkaptonuria?

(a) 0

(b) 1/4 -------------------------answer

(c) 1/12

(d) 1/16