What cofactors would you predict you would need for the over

What co-factors would you predict you would need for the overall reaction and why?

Phosphocreatine ----------> Creatine + Pi

ATP ----------> ADP + Pi

Solution

Magnesium ions, Mg²⁺ serve as cofactors in the overall reaction. Mg²⁺ ions complex helps in aligning the substrates and helps in the transfer of the inorganic phosphate molecule from ATP to Creatine molecule.