Rank these reactions from least to most energetically favora

Rank these reactions from least to most energetically favorable.

Solution

In a chemical reaction, energetically favorable means that the process or reaction does not require an extra input of energy during the reaction.Chemically the process contains a negative change in Gibbs free energy. Therefore, the order of reactions from least to most favorable are as follows:

1. Glucose to Glucose-6-P, +3.3kcal/mol

2. Glucose-6-P to Fructose-6-P, +0.4kcal/mol

3. ATP to ADP and Pi, -7.3kcal/mol

4. PEP to pyruvate, -14.8kcal/mol