1DNA Synthesis occurs in the A 5 to 3 direction B 5 to 2 dir

1.DNA Synthesis occurs in the

A. 5\' to 3\' direction.

B. 5\' to 2\' direction.

C. 3\' to 2\' direction.

D. 3\' to 5\' direction.

2 Very few proteins are degraded via the 26S proteosome.

True

False

3 Proteins are modified while they are being synthesized.

True

False

4 Which of the following statements is FALSE?

A. Genes are always immutably fixed on a chromosome.

B. Several slightly different mRNAs can be made form the same gene.

C. Some RNA, like rRNA, have catalytic activity.

D. Mature mRNA strands are generally shorter than the gene from which they are transcribed.

5 Select the correct terms to complete the following sentence: Sickle cell anemia is the result of a single base mutation in the DNA sequence for beta-globin. This, in turn, results in a change in in one amino acid from the category of [1.Polar (hydrophilic) 2.Hydrophobic 3.Basic 4.Acidic] to the category of [1.Polar (hydrophilic) 2.Hydrophobic 3.Basic 4.Acidic].

6.Which of the following statements is FALSE?

A. The Lagging strand is synthesized as Okazaki fragments

B. DNA polymerases need a primer to start DNA synthesis

C. A primer is made from RNA

D. The Lagging strand is synthesized in the same direction as the Leading strand.

7 There is redundancy in the genetic code. This means that....... (Choose ALL that apply)

A. For most amino acids there is more than one Codon.

B. The third nucleotide in the sequence is unimportant.

C. There must be a tRNA for each Codon.

D. Changes in the DNA sequence for some Codons may not affect the protein sequence

8. mRNA and tRNA are both synthesized by the same RNA polymerase.

True

False

9 Peptide bond formation requires the addition of a water molecule to the amino acids involved.

True

False

10 What does EF-Tu do?

A. It terminates translation.

B. It ensures that the proper tRNA enters the A site.

C. It carries a GTP into the ribosome and enables the ribosome to slide doen the mRNA molecule.

D. It binds to f-Met-tRNA and a molecule of GTP and together they form the ternary complex.

Solution

1.DNA Synthesis occurs in the
A. 5\' to 3\' direction.

2 Very few proteins are degraded via the 26S proteosome.
False

3 Proteins are modified while they are being synthesized.
False

4 Which of the following statements is FALSE?
A. Genes are always immutably fixed on a chromosome.

5 Select the correct terms to complete the following sentence: Sickle cell anemia is the result of a single base mutation in the DNA sequence for beta-globin. This, in turn, results in a change in in one amino acid from the category of [1.Polar (hydrophilic) 2.Hydrophobic 3.Basic 4.Acidic] to the category of [1.Polar (hydrophilic) 2.Hydrophobic 3.Basic 4.Acidic].

Glutamic acid to valine
Hydrophilic to hydrophobic

6.Which of the following statements is FALSE?
D. The Lagging strand is synthesized in the same direction as the Leading strand.

7 There is redundancy in the genetic code. This means that....... (Choose ALL that apply)
A. For most amino acids there is more than one Codon.
B. The third nucleotide in the sequence is unimportant.

8. mRNA and tRNA are both synthesized by the same RNA polymerase.
False - mRNA is synthesized by RNA Poly II and tRNA is synthesized by RNA pol III

9 Peptide bond formation requires the addition of a water molecule to the amino acids involved.
False - In peptide bond formation water molecule released